Cellular and molecular analysis of plasmodium development in Physarum

Juliet Bailey, Lilianna Solnica-Krezel, Karin Lohman, Jennifer Dee, Roger W. Anderson, William F. Dove

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The development of an amoeba into a plasmodium involves extensive changes in cellular organisation and gene expression. The genetic basis of a number of recessive mutations that block plasmodium development has been elucidated. The stage at which development becomes abnormal has been determined for all the mutants, as has the terminal phenotype. In order to investigate the changes in gene expression that accompany plasmodium development, a cDNA library has been made using RNA isolated from cell populations in which development was occurring.

Original languageEnglish
Pages (from-to)1083-1090
Number of pages8
JournalCell Biology International Reports
Issue number11
StatePublished - 1992


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