Abstract
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan. Multiple genetic approaches have defined a chitosandeficient syndrome that includes slow growth and decreased cell integrity. Here we demonstrate chitosan is necessary for virulence and persistence in the mammalian host.
| Original language | English |
|---|---|
| Pages (from-to) | 1264-1268 |
| Number of pages | 5 |
| Journal | Eukaryotic Cell |
| Volume | 10 |
| Issue number | 9 |
| DOIs |
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| State | Published - Sep 1 2011 |
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Baker, L. G., Specht, C. A., & Lodge, J. K. (2011). Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryotic Cell, 10(9), 1264-1268. https://doi.org/10.1128/EC.05138-11