Abstract
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan. Multiple genetic approaches have defined a chitosandeficient syndrome that includes slow growth and decreased cell integrity. Here we demonstrate chitosan is necessary for virulence and persistence in the mammalian host.
Original language | English |
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Pages (from-to) | 1264-1268 |
Number of pages | 5 |
Journal | Eukaryotic Cell |
Volume | 10 |
Issue number | 9 |
DOIs |
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State | Published - Sep 2011 |