@article{38a7a1ec8eb4482a940e726cd7d7417f,
title = "Cell type-specific dendritic polarity in the absence of spatially organized external cues",
abstract = "Pyramidal neurons of the hippocampus and cortex have polarized dendritic arbors, but little is known about the cellular mechanisms distinguishing apical and basal dendrites. We used morphometric analysis and time lapse imaging of cultured hippocampal neurons to show that glutamatergic neurons develop progressive dendritic asymmetry in the absence of polarized extrinsic cues. Thus, pyramidal neurons have a cellular program for polarized dendrite growth independent of tissue microenvironment.",
author = "Horton, {April C.} and Yi, {Jason J.} and Ehlers, {Michael D.}",
note = "Funding Information: We thank Irina Lebedeva and Haiwei Zhang for expert technical assistance, and Pavel Osten for providing the lentivirus GFP constructs. We thank Tom Blanpied, Kathryn Condon, David Fitzpatrick, Juliet Hernandez, Larry Katz, Shannon LaDeau, Jennifer Dewar, and Eric Monson for helpful comments on the manuscript. This work was supported by grants to MDE from the NIH, the Christopher Reeve Paralysis Foundation, and the Raymond and Beverly Sackler Foundation, to ACH from the Triangle Community Foundation, and to JJY from the Ruth K. Broad Foundation. MDE is an Investigator of the Howard Hughes Medical Institute.",
year = "2006",
month = feb,
doi = "10.1007/s11068-006-9003-y",
language = "English",
volume = "35",
pages = "29--38",
journal = "Brain Cell Biology",
issn = "1559-7105",
number = "1",
}