Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa

Keyphrases

• Functional Characterization 100%
• Trypanosomatid Protozoa 100%
• Cell-free Protein Synthesis 100%
• Synthesis, Characterization 100%
• Sphingolipid Synthase 100%
• Phosphatidylinositol Synthase 66%
• Bifunctional 66%
• Enzymatic Specificity 66%
• Cell-free Synthesis System 66%
• Ethanolamine 66%
• Inositol Phosphorylceramide 66%
• Cell Behavior 33%
• Liposomes 33%
• First Application 33%
• Orthologs 33%
• Bloodstream 33%
• Potent Inhibitor 33%
• Integral Membrane Protein 33%
• Site-directed mutagenesis 33%
• Protozoan Parasites 33%
• Gene Family 33%
• Putative Drug Targets 33%
• Highly Similar 33%
• Functional Annotation 33%
• Trypanosoma Brucei 33%
• Sphingomyelin 33%
• Phylogenetic Distance 33%
• Enzyme System 33%
• Reaction Conditions 33%
• Insect Stage 33%
• Array Data 33%
• Similar Genes 33%
• Trypanosoma Cruzi (T. cruzi) 33%
• Expression Array 33%
• Aureobasidin A 33%
• Polymorphic Membrane Proteins 33%
• Rapid Optimization 33%
• Product Specificity 33%
• Rapid Preparation 33%
• Gene Encoding 33%

Medicine and Dentistry

• Synthetase 100%
• Protozoa 100%
• Sphingolipid 100%
• Trypanosomatid 100%
• Inositol 66%
• Membrane Protein 33%
• Parasite (Microbiology) 33%
• Enzyme Specificity 33%
• Ethanolamine 33%
• Liposome 16%
• Multigene Family 16%
• Orthology 16%
• Site-Directed Mutagenesis 16%
• Enzymes 16%
• Expression Array 16%
• Sphingomyelin 16%
• Aureobasidin A 16%
• Trypanosoma Cruzi 16%
• Trypanosoma Brucei 16%

Biochemistry, Genetics and Molecular Biology

• Synthase 100%
• Trypanosomatidae 100%
• Sphingolipid 100%
• Protozoan 100%
• Inositol 66%
• Enzyme 33%
• Enzyme Specificity 33%
• Parasite 33%
• Membrane Protein 16%
• Multigene Family 16%
• Orthology 16%
• Site-Directed Mutagenesis 16%
• Trypanosoma Brucei 16%
• Integral Membrane Protein 16%
• Trypanosoma Cruzi 16%
• Cladistics 16%
• Sphingomyelin 16%