Recent work on cell division and chromosome orientation and partitioning in Bacillus subtilis has provided insights into cell cycle regulation during growth and development. The cell cycle is an integral part of development and entrance into sporulation is modulated by signals that transmit the status of DNA integrity, chromosome replication and segregation. In addition, B. subtilis modifies cell division and DNA segregation to establish cell-type-specific gene expression during sporulation.

Original languageEnglish
Pages (from-to)630-635
Number of pages6
JournalCurrent Opinion in Microbiology
Issue number6
StatePublished - Dec 1998


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