Ceftolozane-tazobactam activity against phylogenetically diverse clostridium difficile strains

Mark D. Gonzalez; Meghan A. Wallace; Tiffany Hink; Erik R. Dubberke; Carey Ann D. Burnham

doi:10.1128/AAC.01670-15

Ceftolozane-tazobactam activity against phylogenetically diverse clostridium difficile strains

Mark D. Gonzalez, Meghan A. Wallace, Tiffany Hink, Erik R. Dubberke, Carey Ann D. Burnham

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Ceftolozane-tazobactam (C/T) is approved for the treatment of complicated intra-abdominal and urinary tract infections and has varied activity against anaerobic bacteria. Here, we evaluate the activity of C/T against a phylogenetically diverse collection of Clostridium difficile isolates and report uniformly high MICs (≥256 μg/ml) to C/T.

Original language	English
Pages (from-to)	7084-7085
Number of pages	2
Journal	Antimicrobial agents and chemotherapy
Volume	59
Issue number	11
DOIs	https://doi.org/10.1128/AAC.01670-15
State	Published - Nov 1 2015

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abstract = "Ceftolozane-tazobactam (C/T) is approved for the treatment of complicated intra-abdominal and urinary tract infections and has varied activity against anaerobic bacteria. Here, we evaluate the activity of C/T against a phylogenetically diverse collection of Clostridium difficile isolates and report uniformly high MICs (≥256 μg/ml) to C/T.",

author = "Gonzalez, {Mark D.} and Wallace, {Meghan A.} and Tiffany Hink and Dubberke, {Erik R.} and Burnham, {Carey Ann D.}",

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AU - Wallace, Meghan A.

AU - Hink, Tiffany

AU - Dubberke, Erik R.

AU - Burnham, Carey Ann D.

PY - 2015/11/1

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AB - Ceftolozane-tazobactam (C/T) is approved for the treatment of complicated intra-abdominal and urinary tract infections and has varied activity against anaerobic bacteria. Here, we evaluate the activity of C/T against a phylogenetically diverse collection of Clostridium difficile isolates and report uniformly high MICs (≥256 μg/ml) to C/T.

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Ceftolozane-tazobactam activity against phylogenetically diverse clostridium difficile strains

Abstract

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