TY - JOUR
T1 - CDEK
T2 - Clinical Drug Experience Knowledgebase
AU - Griesenauer, Rebekah H.
AU - Schillebeeckx, Constantino
AU - Kinch, Michael S.
N1 - Funding Information:
The authors would like to acknowledge Tom Krenning for the initial conceptualizations of CDEK. Research reported in this publication was supported by the Washington University Institute of Clinical and Translational Sciences grant UL1TR002345, sub-award TL1TR002344, from the NCATS of the NIH. The content is solely the responsibility of the authors and does not necessarily represent the official view of the NIH.
Publisher Copyright:
© 2019 The Author(s) 2019. Published by Oxford University Press.
PY - 2019
Y1 - 2019
N2 - The Clinical Drug Experience Knowledgebase (CDEK) is a database and web platform of active pharmaceutical ingredients with evidence of clinical testing as well as the organizations involved in their research and development. CDEK was curated by disambiguating intervention and organization names from ClinicalTrials.gov and cross-referencing these entries with other prominent drug databases. Approximately 43% of active pharmaceutical ingredients in the CDEK database were sourced from ClinicalTrials.gov and cannot be found in any other prominent compound-oriented database. The contents of CDEK are structured around three pillars: active pharmaceutical ingredients (n = 22 292), clinical trials (n = 127 223) and organizations (n = 24 728). The envisioned use of the CDEK is to support the investigation of many aspects of drug development, including discovery, repurposing opportunities, chemo-and bio-informatics, clinical and translational research and regulatory sciences.
AB - The Clinical Drug Experience Knowledgebase (CDEK) is a database and web platform of active pharmaceutical ingredients with evidence of clinical testing as well as the organizations involved in their research and development. CDEK was curated by disambiguating intervention and organization names from ClinicalTrials.gov and cross-referencing these entries with other prominent drug databases. Approximately 43% of active pharmaceutical ingredients in the CDEK database were sourced from ClinicalTrials.gov and cannot be found in any other prominent compound-oriented database. The contents of CDEK are structured around three pillars: active pharmaceutical ingredients (n = 22 292), clinical trials (n = 127 223) and organizations (n = 24 728). The envisioned use of the CDEK is to support the investigation of many aspects of drug development, including discovery, repurposing opportunities, chemo-and bio-informatics, clinical and translational research and regulatory sciences.
UR - http://www.scopus.com/inward/record.url?scp=85071282015&partnerID=8YFLogxK
U2 - 10.1093/database/baz087
DO - 10.1093/database/baz087
M3 - Article
C2 - 31411687
AN - SCOPUS:85071282015
SN - 1758-0463
VL - 2019
JO - Database
JF - Database
IS - 1
M1 - baz087
ER -