Cat-Map: Putting cataract on the map

Alan Shiels, Thomas M. Bennett, J. Fielding Hejtmancik

Research output: Contribution to journalArticlepeer-review

212 Scopus citations

Abstract

Lens opacities, or cataract(s), may be inherited as a classic Mendelian disorder usually with early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many genetic forms of cataract have been described in mice and other animal models. Considerable progress has been made in mapping and identifying the genes and mutations responsible for inherited forms of cataract, and genetic determinants of age-related cataract are beginning to be discovered. To provide a convenient and accurate summary of current information focused on the increasing genetic complexity of Mendelian and age-related cataract we have created an online chromosome map and reference database for cataract in humans and mice (Cat-Map).

Original languageEnglish
Pages (from-to)2007-2015
Number of pages9
JournalMolecular vision
Volume16
StatePublished - 2010

Fingerprint

Dive into the research topics of 'Cat-Map: Putting cataract on the map'. Together they form a unique fingerprint.

Cite this