@article{24de4c2823a148d79d1a0560a50c842c,
title = "Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma",
abstract = "An 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography–computed tomography (PET/CT) scan was performed using 2-deoxy-2-[18F]-fluorodeoxyglucose (18F-FDG) to assess for evidence of disease in other locations to guide treatment. Multifocal increased radiopharmaceutical uptake was identified, indicating disease in multiple organs. High-grade lymphoma was confirmed on tissue biopsy. As such, systemic cytotoxic chemotherapy was recommended instead of lymph node extirpation surgery. The cat received a modified CHOP chemotherapy protocol and attained a temporary partial remission. After 2 months of treatment, the cat stopped responding to chemotherapy and was eventually euthanized due to a relapse of disease and decreased quality of life. This case describes the utility of PET/CT to guide treatment in a cat with a presentation consistent with Hodgkin's-like lymphoma.",
keywords = "Hodgkin's, PET/CT, chemotherapy, fluorodeoxiglucose F18, lymphadenopathy, lymphoma",
author = "Chen, \{Carolyn L.\} and Cook, \{Matthew R.\} and Brown, \{Megan E.\} and Sarah Lumbrezer-Johnson and Hostnik, \{Eric T.\} and Lapsley, \{Janis M.\} and Phillip Lerche and Wavreille, \{Vincent A.\} and Menendez, \{Maria I.\} and Knopp, \{Michael V.\} and Linn, \{Sarah C.\} and Christopher Premanandan and Selmic, \{Laura E.\}",
note = "Funding Information: The authors would like to thank the Wright Center of Innovation in Biomedical Imaging and their staff at The Ohio State University Wexner Medical Center for their expertise and help performing the PET/CT. The authors would also like to thank The Ohio State University Comparative Pathology and Mouse Phenotyping Shared Resource for histopathology and immunohistochemistry along with UC-Davis Leukocyte Antigen Biology Laboratory's pathologists Peter F. Moore BVSc, Ph.D., DACVP and William Vernau, BSc, BVMS, DVSc, Ph.D., DACVP for their diagnosis and interpretation of the biopsy specimen. Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 Chen, Cook, Brown, Lumbrezer-Johnson, Hostnik, Lapsley, Lerche, Wavreille, Menendez, Knopp, Linn, Premanandan and Selmic.",
year = "2021",
month = apr,
day = "29",
doi = "10.3389/fvets.2021.619264",
language = "English",
volume = "8",
journal = "Frontiers in Veterinary Science",
issn = "2297-1769",
}