Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Transcription Factors 100%
• Cell Cycle Progression 100%
• Carnitine O-Palmitoyltransferase 100%
• Beta Oxidation 75%
• Carcinogenesis 50%
• Lipolysis 50%
• Lipogenesis 50%
• Enzyme 25%
• Cyclin-Dependent Kinase 25%
• Cell Cycle Arrest 25%
• Overall Survival 25%
• Adenosine Triphosphate 25%
• Cell Cycle 25%
• Acyl-CoA 25%
• Carnitine Palmitoyltransferase I 25%
• Cell Cycle Regulation 25%
• AMP-activated Protein Kinase 25%
• Anchorage Independent Growth 25%
• Cell Cycle Checkpoint 25%
• Mitochondrial Matrix 25%
• P38 Mitogen-Activated Protein Kinases 25%
• Deficiency 25%

Keyphrases

• Ovarian Cancer 100%
• Cell Cycle Progression 100%
• Carnitine Palmitoyltransferase 1A (CPT1A) 100%
• FoxO Transcription Factors 100%
• Ovarian Cancer Cells 30%
• Fatty Acid Oxidation 30%
• Lipid Catabolism 20%
• P21Cip1 20%
• Mitogen-activated Protein Kinase 10%
• Overexpression 10%
• Cyclin-dependent Kinase Inhibitor 10%
• Cell Cycle Arrest 10%
• Therapeutic Intervention 10%
• Overall Survival 10%
• Fatty Acids 10%
• Cancer Cells 10%
• Malignancy 10%
• In Cancer 10%
• Ovarian Cancer Patients 10%
• Xenograft 10%
• Cell Cycle Regulation 10%
• Prognostic Biomarker 10%
• Oncogenic Process 10%
• Lipogenesis 10%
• Rate-limiting Enzyme 10%
• Fatty Acid Synthesis 10%
• Acyl Groups 10%
• ATP Level 10%
• L-carnitine 10%
• AMP-activated Protein Kinase 10%
• Anchorage-independent Growth 10%
• Cell Cycle Regulators 10%
• Mitochondrial Matrix 10%
• Cellular ATP 10%
• Ovarian Serous Carcinoma 10%
• Acyl-CoA Esters 10%