TY - JOUR
T1 - Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic
AU - Ryan, John J.
AU - Melendres-Groves, Lana
AU - Zamanian, Roham T.
AU - Oudiz, Ronald J.
AU - Chakinala, Murali
AU - Rosenzweig, Erika B.
AU - Gomberg-Maitland, Mardi
N1 - Funding Information:
This manuscript was written with support provided by Elizabeth Joseloff, PhD at the Pulmonary Hypertension Association (PHA). The authors wish to acknowledge Jennalyn Mayeux, DNP who reviewed an earlier version of this manuscript.
Funding Information:
Dr Ryan and his research is supported by funding from The Reagan Corporation, The Gordon Family, and The Cushman Family.
Publisher Copyright:
© The Author(s) 2020.
PY - 2020/4
Y1 - 2020/4
N2 - The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary arterial hypertension, where pulmonary arterial hypertension-specific treatments are used. It is important to balance the ongoing care and evaluation of pulmonary arterial hypertension patients with “exposure risk” to COVID-19 for patients coming to clinic or the hospital. If there is a morbidity and mortality benefit from starting pulmonary arterial hypertension therapies, for example in a patient with high-likelihood of pulmonary arterial hypertension, then it remains important to complete the thorough evaluation. However, the COVID-19 outbreak may also represent a unique time when pulmonary hypertension experts have to weigh the risks and benefits of the diagnostic work-up including potential exposure to COVID-19 versus initiating targeted pulmonary arterial hypertension therapy in a select high-risk, high likelihood World Symposium Pulmonary Hypertension Group 1 pulmonary arterial hypertension patients. This document will highlight some of the issues facing providers, patients, and the pulmonary arterial hypertension community in real-time as the COVID-19 pandemic is evolving and is intended to share expected common clinical scenarios and best clinical practices to help the community at-large.
AB - The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary arterial hypertension, where pulmonary arterial hypertension-specific treatments are used. It is important to balance the ongoing care and evaluation of pulmonary arterial hypertension patients with “exposure risk” to COVID-19 for patients coming to clinic or the hospital. If there is a morbidity and mortality benefit from starting pulmonary arterial hypertension therapies, for example in a patient with high-likelihood of pulmonary arterial hypertension, then it remains important to complete the thorough evaluation. However, the COVID-19 outbreak may also represent a unique time when pulmonary hypertension experts have to weigh the risks and benefits of the diagnostic work-up including potential exposure to COVID-19 versus initiating targeted pulmonary arterial hypertension therapy in a select high-risk, high likelihood World Symposium Pulmonary Hypertension Group 1 pulmonary arterial hypertension patients. This document will highlight some of the issues facing providers, patients, and the pulmonary arterial hypertension community in real-time as the COVID-19 pandemic is evolving and is intended to share expected common clinical scenarios and best clinical practices to help the community at-large.
KW - clinical trials
KW - mechanical ventilation
KW - prostacyclin
KW - pulmonary hypertension
KW - right heart failure
KW - therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85086266693&partnerID=8YFLogxK
U2 - 10.1177/2045894020920153
DO - 10.1177/2045894020920153
M3 - Article
C2 - 32426111
AN - SCOPUS:85086266693
SN - 2045-8932
VL - 10
JO - Pulmonary Circulation
JF - Pulmonary Circulation
IS - 2
ER -