TY - JOUR
T1 - Cardiovascular Disease in Rheumatoid Arthritis
AU - Sen, Deepali
AU - González-Mayda, María
AU - Brasington, Richard D.
PY - 2014/2
Y1 - 2014/2
N2 - Cardiovascular disease causes significant morbidity and mortality in rheumatoid arthritis (RA). Accelerated atherosclerosis caused by inflammation is the hallmark of cardiovascular disease in RA. Cardiac involvement as an extra-articular manifestation of RA is also prevalent but often subclinical. Treatment of RA also has implications on cardiovascular outcomes in RA. In this article, atherosclerotic and nonatherosclerotic cardiac manifestations in RA are discussed, with a focus on pathogenesis and management.
AB - Cardiovascular disease causes significant morbidity and mortality in rheumatoid arthritis (RA). Accelerated atherosclerosis caused by inflammation is the hallmark of cardiovascular disease in RA. Cardiac involvement as an extra-articular manifestation of RA is also prevalent but often subclinical. Treatment of RA also has implications on cardiovascular outcomes in RA. In this article, atherosclerotic and nonatherosclerotic cardiac manifestations in RA are discussed, with a focus on pathogenesis and management.
KW - Atherosclerosis
KW - Cardiovascular disease
KW - Inflammation
KW - Management
KW - Rheumatoid arthritis
UR - http://www.scopus.com/inward/record.url?scp=84888198987&partnerID=8YFLogxK
U2 - 10.1016/j.rdc.2013.10.005
DO - 10.1016/j.rdc.2013.10.005
M3 - Review article
C2 - 24268008
AN - SCOPUS:84888198987
SN - 0889-857X
VL - 40
SP - 27
EP - 49
JO - Rheumatic Disease Clinics of North America
JF - Rheumatic Disease Clinics of North America
IS - 1
ER -