Cardiovascular Disease in Rheumatoid Arthritis

Deepali Sen, María González-Mayda, Richard D. Brasington

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Cardiovascular disease causes significant morbidity and mortality in rheumatoid arthritis (RA). Accelerated atherosclerosis caused by inflammation is the hallmark of cardiovascular disease in RA. Cardiac involvement as an extra-articular manifestation of RA is also prevalent but often subclinical. Treatment of RA also has implications on cardiovascular outcomes in RA. In this article, atherosclerotic and nonatherosclerotic cardiac manifestations in RA are discussed, with a focus on pathogenesis and management.

Original languageEnglish
Pages (from-to)27-49
Number of pages23
JournalRheumatic Disease Clinics of North America
Issue number1
StatePublished - Feb 2014


  • Atherosclerosis
  • Cardiovascular disease
  • Inflammation
  • Management
  • Rheumatoid arthritis


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