Cardiac resynchronization therapy: What? Who? When? How?

Phillip S. Cuculich, Susan Joseph

Research output: Contribution to journalComment/debate

7 Scopus citations


Cardiac resynchronization therapy is an important and underused tool to help patients with heart failure symptoms, left ventricular systolic dysfunction (LVEF ≤ 35%), and intraventricular conduction system disease (QRS < 120 msec). Cardiac resynchronization therapy paces the heart simultaneously from both right and left ventricles (through the coronary sinus). Approximately three quarters of patients who undergo a successful implant will have some degree of symptomatic improvement and have fewer heart failure hospitalizations. When cardiac resynchronization therapy is combined with a defibrillator, patients may benefit from the added protection against sudden arrhythmic death.

Original languageEnglish
Pages (from-to)813-815
Number of pages3
JournalAmerican Journal of Medicine
Issue number9
StatePublished - Sep 2011


  • Biventricular pacing
  • Cardiac device
  • Cardiac resynchronization therapy
  • Heart failure


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