Carcinoid Arising from the Teratomatous Bronchial Mucosa in a Mature Cystic Teratoma of the Ovary: A Case Report

Dongfeng Niu, Zhongwu Li, Li Sun, Dengfeng Cao

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1 Scopus citations

Abstract

Primary ovarian carcinoids are relatively uncommon, either pure (monodermal teratomas) or in association with mature cystic teratomas. Here we reported a unique case of carcinoid arising from the teratomatous bronchial mucosa in an ovarian mature cystic teratoma in a 22-year-old woman. This tumor showed a compact trabecular and nested growth pattern with salt-and-pepper chromatin pattern. Mitotic figures were identified (6/10 high power fields) and focal necrosis was present. Immunohistochemically the tumor cells were diffusely positive for TTF1 and CD56, focally positive for synaptophysin, and negative for chromogranin A and CDX2. Ki67 proliferation index was approximately 20% to 25%. This patient was alive with no evidence of disease at 3 years and 7 months after surgery. To our knowledge, this is the first case report of carcinoid arising from the teratomatous bronchial mucosa in an ovarian mature teratoma in the English literature.

Original languageEnglish
Pages (from-to)123-127
Number of pages5
JournalInternational Journal of Gynecological Pathology
Volume37
Issue number2
DOIs
StatePublished - Jan 1 2018

Keywords

  • Bronchial mucosa
  • Carcinoid
  • Mature cystic teratoma
  • Ovary

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