TY - JOUR
T1 - Carboxyethyl γ - Aminobutyric Acid, a polyamine derivative, improves the recovery of EBV-transformed lymphocytes
AU - Cerino, Antonella
AU - Bestagno, Marco
AU - Colonna, Marco
AU - Fussi, Fernando
AU - Astaldi Ricotti, Giulia C.B.
PY - 1988/2/15
Y1 - 1988/2/15
N2 - A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the stability of EBV-transformed cell lines over time, and does not affect the growth of stabilized cell lines. It is possible that CEGABA acts on cells other than EBV transformed lymphocytes (in fact, after EBV infection all types of mononuclear cells from the blood are present in the culture) and indirectly promotes the growth of EBV transformed lymphocytes.
AB - A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the stability of EBV-transformed cell lines over time, and does not affect the growth of stabilized cell lines. It is possible that CEGABA acts on cells other than EBV transformed lymphocytes (in fact, after EBV infection all types of mononuclear cells from the blood are present in the culture) and indirectly promotes the growth of EBV transformed lymphocytes.
UR - http://www.scopus.com/inward/record.url?scp=0023869899&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(88)90718-8
DO - 10.1016/0006-291X(88)90718-8
M3 - Article
C2 - 2829900
AN - SCOPUS:0023869899
SN - 0006-291X
VL - 150
SP - 931
EP - 936
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -