The 13C NMR resonances of the secosteroids la, 2a, and 3a have been assigned by reference to known models and appropriately deuterated derivatives. A dynamic NMR study of 2a shows an unexpected broadening of the resonances of C-l, -9, and -10 which is attributed to an intramolecular hydrogen bond between the C-10 carbonyl and the C-3 hydroxyl group. This conclusion is supported by studies of solvent effects upon the proton and 13C NMR and infrared spectra.
|Number of pages||4|
|Journal||Journal of Organic Chemistry|
|State||Published - Aug 1980|