TY - JOUR
T1 - Calpain regulated cell adhesion in EGF-stimulated fibroblast-populated-collagen-lattice contraction
AU - Allen, Fred D.
AU - Asnes, Clara F.
AU - Chang, Philip
AU - Elson, Elliot L.
AU - Lauffenburger, Douglas A.
AU - Wells, Alan
PY - 2001
Y1 - 2001
N2 - Calpain regulated cell adhesion in EGF-stimulated fibroblast-populated-collagen-lattice (FPCL) contraction was investigated. It was shown that fibroblasts capable of EGF/EGFR signaling rapidly generate significant and transient contractile force in response to EGF stimulation. Results also showed that calpain plays an important role in the transfer of that force to the extracellular collagen matrix by modulating cell-matrix adhesion.
AB - Calpain regulated cell adhesion in EGF-stimulated fibroblast-populated-collagen-lattice (FPCL) contraction was investigated. It was shown that fibroblasts capable of EGF/EGFR signaling rapidly generate significant and transient contractile force in response to EGF stimulation. Results also showed that calpain plays an important role in the transfer of that force to the extracellular collagen matrix by modulating cell-matrix adhesion.
UR - http://www.scopus.com/inward/record.url?scp=0242441594&partnerID=8YFLogxK
M3 - Conference article
AN - SCOPUS:0242441594
SN - 1071-6947
VL - 50
SP - 353
EP - 354
JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
JF - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
T2 - Proceedings of the 2001 Bioengineering Conference
Y2 - 27 June 2001 through 1 July 2001
ER -