Calibrated real-time control of lesion size based on reflectance images

Maya R. Jerath, Danielle Kaisig, H. Grady Rylander, Ashley J. Welch

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Lesion size induced by laser photocoagulation is controlled in real time based on a two-dimensional reflectance image recorded by a CCD array during lesion formation. A feedback system using components of the reflectance image achieves uniform lesions by compensating for light absorption variability in biological media. Lesions are formed in a phantom by an argon laser to simulate retinal photocoagulation. The tissue model consists of a thin absorptive layer covered by a clear albumin protein layer. Results show a low variance in the sizes of the lesions (diameter or depth) produced in different irradiation conditions and the ability to produce lesions of a predefined size in varying illumination conditions.

Original languageEnglish
Pages (from-to)1200-1209
Number of pages10
JournalApplied Optics
Issue number7
StatePublished - Mar 1993


  • Feedback
  • Laser
  • Photocoagulation
  • Reflectance


Dive into the research topics of 'Calibrated real-time control of lesion size based on reflectance images'. Together they form a unique fingerprint.

Cite this