Calcium, Magnesium, and Vitamin D Absorption; Metabolim and Deficiency

Roberto Civitelli; Konstantinos Ziambaras; Wendy E. Ward

doi:10.1016/B978-0-12-801238-3.66113-5

Calcium, Magnesium, and Vitamin D Absorption; Metabolim and Deficiency

Roberto Civitelli, Konstantinos Ziambaras, Wendy E. Ward

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

Abstract

In terrestrial vertebrates, mineral homeostasis involves intestine, kidney, and bone and is regulated primarily by parathyroid hormone (PTH) and 1α,25 (OH)2D, the biologically active, hormonal form of vitamin D. The concentration of calcium ions in the circulation is maintained within a narrow range; increased absorption of Ca2+ in the intestine and decreased excretion of Ca2+ by the kidney are usually sufficient to maintain calcium balance; however, under conditions of severe calcium deficiency, Ca2+ is mobilized from bone. The concentration of serum magnesium is regulated primarily by the kidney and magnesium is involved in the synthesis of PTH.

Original language	English
Title of host publication	Encyclopedia of Gastroenterology, Second Edition
Publisher	Elsevier
Pages	418-423
Number of pages	6
ISBN (Electronic)	9780128124604
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.66113-5
State	Published - Jan 1 2019

Keywords

1α,25 (OH)D
Bone
Calcium
FRAX®
Magnesium
Osteoporosis
Parathyroid hormone
Peak bone mass
Recommended dietary allowance
Vitamin D

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10.1016/B978-0-12-801238-3.66113-5

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abstract = "In terrestrial vertebrates, mineral homeostasis involves intestine, kidney, and bone and is regulated primarily by parathyroid hormone (PTH) and 1α,25 (OH)2D, the biologically active, hormonal form of vitamin D. The concentration of calcium ions in the circulation is maintained within a narrow range; increased absorption of Ca2+ in the intestine and decreased excretion of Ca2+ by the kidney are usually sufficient to maintain calcium balance; however, under conditions of severe calcium deficiency, Ca2+ is mobilized from bone. The concentration of serum magnesium is regulated primarily by the kidney and magnesium is involved in the synthesis of PTH.",

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AU - Civitelli, Roberto

AU - Ziambaras, Konstantinos

AU - Ward, Wendy E.

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AB - In terrestrial vertebrates, mineral homeostasis involves intestine, kidney, and bone and is regulated primarily by parathyroid hormone (PTH) and 1α,25 (OH)2D, the biologically active, hormonal form of vitamin D. The concentration of calcium ions in the circulation is maintained within a narrow range; increased absorption of Ca2+ in the intestine and decreased excretion of Ca2+ by the kidney are usually sufficient to maintain calcium balance; however, under conditions of severe calcium deficiency, Ca2+ is mobilized from bone. The concentration of serum magnesium is regulated primarily by the kidney and magnesium is involved in the synthesis of PTH.

KW - 1α,25 (OH)D

KW - Bone

KW - Calcium

KW - FRAX®

KW - Magnesium

KW - Osteoporosis

KW - Parathyroid hormone

KW - Peak bone mass

KW - Recommended dietary allowance

KW - Vitamin D

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DO - 10.1016/B978-0-12-801238-3.66113-5

M3 - Chapter

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SP - 418

EP - 423

BT - Encyclopedia of Gastroenterology, Second Edition

PB - Elsevier

ER -

Calcium, Magnesium, and Vitamin D Absorption; Metabolim and Deficiency

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