Cadaveric nerve allotransplantation in the treatment of persistent thoracic neuralgia

John R. Barbour, Andrew Yee, Amy M. Moore, Elbert P. Trulock, Jacob M. Buchowski, Susan E. Mackinnon

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

When relief from neuralgia cannot be achieved with traditional methods, neurectomy may be considered to abate the stimulus, and primary opposition of the terminal nerve ending is recommended to prevent neuroma. Nerve repair with autograft is limited by autologous nerves available for large nerve defects. Cadaveric allografts provide an unlimited graft source without donor-site morbidities, but are rapidly rejected unless appropriate immunosuppression is achieved. An optimal treatment method for nerve allograft transplantation would minimize rejection while simultaneously permitting nerve regeneration. This report details a novel experience of nerve allograft transplantation using cadaveric nerve grafts to desensitize persistent postoperative thoracic neuralgia.

Original languageEnglish
Pages (from-to)1414-1417
Number of pages4
JournalAnnals of Thoracic Surgery
Volume99
Issue number4
DOIs
StatePublished - Apr 1 2015

Fingerprint Dive into the research topics of 'Cadaveric nerve allotransplantation in the treatment of persistent thoracic neuralgia'. Together they form a unique fingerprint.

  • Cite this