C5a receptor activation: Genetic identification of critical residues in four transmembrane helices

Keyphrases

• Activating mutation 33%
• Activating Receptors 33%
• Amino Acid Position 33%
• Amino Acid Substitution 66%
• Amino Acids 33%
• C5a Receptor 100%
• Chemoattractant 33%
• Constitutive Behavior 33%
• Coreceptor Switch 66%
• G Protein 33%
• General Mechanism 33%
• Genetic Identification 100%
• Helical Surface 33%
• Helix 100%
• Helix Bundle 33%
• Heterotrimeric Guanine nucleotide-binding Protein 33%
• Hormone Stimuli 33%
• Hydrophobic Residues 33%
• III-V 33%
• Lipids 33%
• Membrane Interface 33%
• Nonconservative 33%
• Receptor Activation 100%
• Saturation mutagenesis 33%
• Sensory Stimuli 33%
• Serpentine Receptor 66%
• Switch Mechanism 33%
• Transmembrane 33%
• Transmembrane Helix 100%
• Yeast Selection 33%

Biochemistry, Genetics and Molecular Biology

• Amino Acid Substitution 100%
• Amino Acids 100%
• C5a Receptor 100%
• G Protein 100%
• Genetic Identification 100%
• Helix Bundle 50%
• Lipid 50%
• Mutagenesis 50%
• Protein G 50%
• Sensory Stimulation 50%
• Transmembrane Receptors 50%