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BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis
Sumit Agarwal
, Farrukh Afaq
, Prachi Bajpai
, Michael Behring
, Hyung Gyoon Kim
, Amith Varambally
, Darshan S. Chandrashekar
, Shajan Peter
, Sameer Al Diffalha
,
Moh’d Khushman
, Andreas Seeber
, Sooryanarayana Varambally
, Upender Manne
Section of Medical Oncology
Siteman Cancer Center
Institute of Clinical and Translational Sciences (ICTS)
Research output
:
Contribution to journal
›
Article
›
peer-review
12
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Scopus citations
Overview
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Keyphrases
Colorectal Cancer
100%
Cancer Metastasis
100%
Cancer Growth
100%
BZIP
100%
Knockdown
16%
Tumor Growth
16%
Tumor Metastasis
16%
Enhancer of Zeste Homolog 2 (EZH2)
16%
Colorectal Cancer Cells
16%
Beta-catenin
16%
C-Myc
8%
Overexpression
8%
RNA-seq Analysis
8%
Cell Proliferation
8%
Metastasis
8%
MRNA Level
8%
Downstream Targets
8%
Patient Survival
8%
Tumor Progression
8%
Human Malignancies
8%
Cell Invasion
8%
Colony Formation
8%
Druggable Targets
8%
Histone Demethylase
8%
Human Colorectal Cancer
8%
Metastatic Colorectal Cancer (mCRC)
8%
Malignant Phenotype
8%
Downstream Molecules
8%
Protein Expression Level
8%
Protein Translation
8%
Colorectal Cancer Progression
8%
Spheroid Formation
8%
Malignant Features
8%
Cell Spheroids
8%
Long Non-coding RNA NEAT1
8%
Long Non-coding RNA MALAT1
8%
P4HA1
8%
MicroRNA-98
8%
Proliferation Invasion
8%
Wnt/β-catenin Signaling Pathway
8%
Biochemistry, Genetics and Molecular Biology
Leucine Zipper
100%
Catenin
25%
Tumor Progression
25%
Cancer Cell
16%
Transcription Factor EZH2
16%
Oncogene C Myc
8%
RNA Sequence
8%
Signal Transduction
8%
Wild Type
8%
Transfection
8%
MicroRNA
8%
Cell Proliferation
8%
Histone Methyltransferase
8%
Colony Formation
8%
Tumor Spheroid
8%
Translation (Protein Synthesis)
8%
Long Noncoding RNA
8%
Protein Expression Level
8%
MALAT1
8%
mRNA Expression Level
8%