Abstract
Recent neurochemical and behavioral observations with the nonbenzodiazepine anxiolytic buspirone raise several issues of importance to neuroscientists. These include: (1) the role of a GABA-benzodiazepine receptor-chloride ionophore complex in the actions of buspirone and other anxiolytics; (2) the involvement of dopaminergi-pathways in mediating anxiety and/or anxiolytic actions; and (3) the existence of a common pre- or postreceptor 'effector system' for buspirone and other antianxiety agents. These issues are critically discussed in light of recent findings.
| Original language | English |
|---|---|
| Pages (from-to) | 40-44 |
| Number of pages | 5 |
| Journal | Journal of Clinical Psychiatry |
| Volume | 43 |
| Issue number | 12 II |
| State | Published - Dec 1 1982 |