Building addressable libraries: The use of "safety-Catch" linkers on microelectrode arrays

Bo Bi; Karl Maurer; Kevin D. Moeller

doi:10.1021/ja109253t

Building addressable libraries: The use of "safety-Catch" linkers on microelectrode arrays

Bo Bi
, Karl Maurer
, Kevin D. Moeller

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A "safety-catch" linker strategy has been used to site-selectively cleave and characterize molecules from a microelectrode array. The linkers are attached to the array by means of an ester and contain either a protected amine or protected alcohol nucleophile that can be released using acid generated at the microelectrodes.

Original language	English
Pages (from-to)	17405-17407
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	132
Issue number	49
DOIs	https://doi.org/10.1021/ja109253t
State	Published - Dec 15 2010

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10.1021/ja109253t

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AB - A "safety-catch" linker strategy has been used to site-selectively cleave and characterize molecules from a microelectrode array. The linkers are attached to the array by means of an ester and contain either a protected amine or protected alcohol nucleophile that can be released using acid generated at the microelectrodes.

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Building addressable libraries: The use of "safety-Catch" linkers on microelectrode arrays

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