Building addressable libraries: Site-selective Suzuki reactions on microelectrode arrays

Libo Hu; Karl Maurer; Kevin D. Moeller

doi:10.1021/ol900056u

Building addressable libraries: Site-selective Suzuki reactions on microelectrode arrays

Libo Hu, Karl Maurer, Kevin D. Moeller

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

A site-selective Suzuki reaction has been developed for use on microelectrode arrays. The reaction conditions employed are similar to those used to achieve site-selective Heck reactions. The reaction can be run with either an aryliodide attached to the surface of the array and an arylboronic acid in solution or with an arylboronic acid attached to the surface of the array and an arylbromide in solution. Both allyl acetate and air are effective confining agents for the reaction. The reactions are compatible with arrays containing either 1024 microelectrodes cm ^-2 or 12 544 microelectrodes cm ^-2.

Original language	English
Pages (from-to)	1273-1276
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	6
DOIs	https://doi.org/10.1021/ol900056u
State	Published - Mar 19 2009

Access to Document

10.1021/ol900056u

Cite this

@article{e15e109f69b04ec9b42cb4540509a922,

title = "Building addressable libraries: Site-selective Suzuki reactions on microelectrode arrays",

abstract = "A site-selective Suzuki reaction has been developed for use on microelectrode arrays. The reaction conditions employed are similar to those used to achieve site-selective Heck reactions. The reaction can be run with either an aryliodide attached to the surface of the array and an arylboronic acid in solution or with an arylboronic acid attached to the surface of the array and an arylbromide in solution. Both allyl acetate and air are effective confining agents for the reaction. The reactions are compatible with arrays containing either 1024 microelectrodes cm -2 or 12 544 microelectrodes cm -2.",

author = "Libo Hu and Karl Maurer and Moeller, {Kevin D.}",

year = "2009",

month = mar,

day = "19",

doi = "10.1021/ol900056u",

language = "English",

volume = "11",

pages = "1273--1276",

journal = "Organic Letters",

issn = "1523-7060",

number = "6",

}

TY - JOUR

T1 - Building addressable libraries

T2 - Site-selective Suzuki reactions on microelectrode arrays

AU - Hu, Libo

AU - Maurer, Karl

AU - Moeller, Kevin D.

PY - 2009/3/19

Y1 - 2009/3/19

N2 - A site-selective Suzuki reaction has been developed for use on microelectrode arrays. The reaction conditions employed are similar to those used to achieve site-selective Heck reactions. The reaction can be run with either an aryliodide attached to the surface of the array and an arylboronic acid in solution or with an arylboronic acid attached to the surface of the array and an arylbromide in solution. Both allyl acetate and air are effective confining agents for the reaction. The reactions are compatible with arrays containing either 1024 microelectrodes cm -2 or 12 544 microelectrodes cm -2.

AB - A site-selective Suzuki reaction has been developed for use on microelectrode arrays. The reaction conditions employed are similar to those used to achieve site-selective Heck reactions. The reaction can be run with either an aryliodide attached to the surface of the array and an arylboronic acid in solution or with an arylboronic acid attached to the surface of the array and an arylbromide in solution. Both allyl acetate and air are effective confining agents for the reaction. The reactions are compatible with arrays containing either 1024 microelectrodes cm -2 or 12 544 microelectrodes cm -2.

UR - http://www.scopus.com/inward/record.url?scp=64049093231&partnerID=8YFLogxK

U2 - 10.1021/ol900056u

DO - 10.1021/ol900056u

M3 - Article

C2 - 19239260

AN - SCOPUS:64049093231

SN - 1523-7060

VL - 11

SP - 1273

EP - 1276

JO - Organic Letters

JF - Organic Letters

IS - 6

ER -

Building addressable libraries: Site-selective Suzuki reactions on microelectrode arrays

Abstract

Access to Document

Other files and links

Fingerprint

Cite this