Building addressable libraries: Site-selective lewis acid (Seandium(III)) catalyzed reactions

Bo Bi; Karl Maurer; Kevin D. Moeller

doi:10.1002/anie.200902350

Building addressable libraries: Site-selective lewis acid (Seandium(III)) catalyzed reactions

Bo Bi
, Karl Maurer
, Kevin D. Moeller

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Reagent confinement: Lewis acid catalyzed reactions have been conducted on arrays with either 1024 or 12 544 microelectrodes cm^-2. A Sc ^III species generated at the electrodes is employed as the Lewis acid, and the reagent is confined to the electrodes through the use of a solutionphase reductant. A multicomponent synthesis of a tetrahydropyran (see scheme), a Diels-Alder reaction, and an esterification reaction are all compatible with this strategy.

Original language	English
Pages (from-to)	5872-5874
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	32
DOIs	https://doi.org/10.1002/anie.200902350
State	Published - Jul 27 2009

Keywords

Diels-Alder reactions
Lewis acids
Microelectrode arrays
Multicomponent reactions
Site-selective synthesis

Access to Document

10.1002/anie.200902350

Cite this

@article{93aaa5c3020a43ababb99f9d2ddcebeb,

title = "Building addressable libraries: Site-selective lewis acid (Seandium(III)) catalyzed reactions",

abstract = "Reagent confinement: Lewis acid catalyzed reactions have been conducted on arrays with either 1024 or 12 544 microelectrodes cm-2. A Sc III species generated at the electrodes is employed as the Lewis acid, and the reagent is confined to the electrodes through the use of a solutionphase reductant. A multicomponent synthesis of a tetrahydropyran (see scheme), a Diels-Alder reaction, and an esterification reaction are all compatible with this strategy.",

keywords = "Diels-Alder reactions, Lewis acids, Microelectrode arrays, Multicomponent reactions, Site-selective synthesis",

author = "Bo Bi and Karl Maurer and Moeller, \{Kevin D.\}",

year = "2009",

month = jul,

day = "27",

doi = "10.1002/anie.200902350",

language = "English",

volume = "48",

pages = "5872--5874",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

number = "32",

}

TY - JOUR

T1 - Building addressable libraries

T2 - Site-selective lewis acid (Seandium(III)) catalyzed reactions

AU - Bi, Bo

AU - Maurer, Karl

AU - Moeller, Kevin D.

PY - 2009/7/27

Y1 - 2009/7/27

N2 - Reagent confinement: Lewis acid catalyzed reactions have been conducted on arrays with either 1024 or 12 544 microelectrodes cm-2. A Sc III species generated at the electrodes is employed as the Lewis acid, and the reagent is confined to the electrodes through the use of a solutionphase reductant. A multicomponent synthesis of a tetrahydropyran (see scheme), a Diels-Alder reaction, and an esterification reaction are all compatible with this strategy.

AB - Reagent confinement: Lewis acid catalyzed reactions have been conducted on arrays with either 1024 or 12 544 microelectrodes cm-2. A Sc III species generated at the electrodes is employed as the Lewis acid, and the reagent is confined to the electrodes through the use of a solutionphase reductant. A multicomponent synthesis of a tetrahydropyran (see scheme), a Diels-Alder reaction, and an esterification reaction are all compatible with this strategy.

KW - Diels-Alder reactions

KW - Lewis acids

KW - Microelectrode arrays

KW - Multicomponent reactions

KW - Site-selective synthesis

UR - https://www.scopus.com/pages/publications/70349914297

U2 - 10.1002/anie.200902350

DO - 10.1002/anie.200902350

M3 - Article

C2 - 19582751

AN - SCOPUS:70349914297

SN - 1433-7851

VL - 48

SP - 5872

EP - 5874

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 32

ER -

Building addressable libraries: Site-selective lewis acid (Seandium(III)) catalyzed reactions

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this