Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer

Nwabundo Nwankwo; Aram Barbaryan; Alaa M. Ali; Nasir Hussain; Raya Saba; Suartcha Prueksaritanond; Aibek E. Mirrakhimov; Teresita Zdunek; Nora Bucher

doi:10.1159/000353888

Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer

Nwabundo Nwankwo, Aram Barbaryan, Alaa M. Ali, Nasir Hussain, Raya Saba, Suartcha Prueksaritanond, Aibek E. Mirrakhimov, Teresita Zdunek, Nora Bucher

Division of Hospital Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.

Original language	English
Pages (from-to)	367-372
Number of pages	6
Journal	Case Reports in Oncology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1159/000353888
State	Published - 2013

Keywords

Breast osteosarcoma
Epithelial breast cancer
Radiation therapy

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10.1159/000353888

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title = "Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer",

abstract = "Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.",

keywords = "Breast osteosarcoma, Epithelial breast cancer, Radiation therapy",

author = "Nwabundo Nwankwo and Aram Barbaryan and Ali, {Alaa M.} and Nasir Hussain and Raya Saba and Suartcha Prueksaritanond and Mirrakhimov, {Aibek E.} and Teresita Zdunek and Nora Bucher",

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TY - JOUR

T1 - Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer

AU - Nwankwo, Nwabundo

AU - Barbaryan, Aram

AU - Ali, Alaa M.

AU - Hussain, Nasir

AU - Saba, Raya

AU - Prueksaritanond, Suartcha

AU - Mirrakhimov, Aibek E.

AU - Zdunek, Teresita

AU - Bucher, Nora

PY - 2013

Y1 - 2013

N2 - Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.

AB - Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.

KW - Breast osteosarcoma

KW - Epithelial breast cancer

KW - Radiation therapy

UR - http://www.scopus.com/inward/record.url?scp=84885655948&partnerID=8YFLogxK

U2 - 10.1159/000353888

DO - 10.1159/000353888

M3 - Article

C2 - 23904847

AN - SCOPUS:84885655948

SN - 1662-6575

VL - 6

SP - 367

EP - 372

JO - Case Reports in Oncology

JF - Case Reports in Oncology

IS - 2

ER -

Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer

Abstract

Keywords

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