TY - JOUR
T1 - Breast Cancer Care in the Elderly Patient
AU - Martin, Grace
AU - Shaughnessy, Elizabeth
N1 - Publisher Copyright:
© 2017, Springer Science+Business Media, LLC.
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Purpose of Review: As women continue to live longer, physicians adapt to treating well-described diseases such as breast cancer. Here we provide a comprehensive evidence-based review of the treatment of breast cancer in the elderly patient. Recent Findings: Previous studies conducted to determine optimal treatment for breast cancer have primarily included younger, healthier women. Despite favorable tumor biology, older women are less likely to receive standard of care treatments relative to breast reconstruction, postoperative radiation, and adjuvant chemotherapy. Frailty is cited as a reason for not offering or receiving therapies. There are no strict definitions of frailty for this specific population, but there are general guidelines for older cancer patients, with a lower specificity than desired. Summary: Treatment recommendations for older women vary little from those for younger women. However, the paucity of data for the older age group within trials raises the question of the basis of evidence. Risks of treatment need to be evaluated relative to life expectancy.
AB - Purpose of Review: As women continue to live longer, physicians adapt to treating well-described diseases such as breast cancer. Here we provide a comprehensive evidence-based review of the treatment of breast cancer in the elderly patient. Recent Findings: Previous studies conducted to determine optimal treatment for breast cancer have primarily included younger, healthier women. Despite favorable tumor biology, older women are less likely to receive standard of care treatments relative to breast reconstruction, postoperative radiation, and adjuvant chemotherapy. Frailty is cited as a reason for not offering or receiving therapies. There are no strict definitions of frailty for this specific population, but there are general guidelines for older cancer patients, with a lower specificity than desired. Summary: Treatment recommendations for older women vary little from those for younger women. However, the paucity of data for the older age group within trials raises the question of the basis of evidence. Risks of treatment need to be evaluated relative to life expectancy.
KW - Adjuvant treatment
KW - Breast cancer
KW - Elderly
KW - Frailty
KW - Older
KW - Surgical treatment
UR - http://www.scopus.com/inward/record.url?scp=85028743647&partnerID=8YFLogxK
U2 - 10.1007/s13670-017-0218-9
DO - 10.1007/s13670-017-0218-9
M3 - Review article
AN - SCOPUS:85028743647
SN - 2196-7865
VL - 6
SP - 139
EP - 148
JO - Current Geriatrics Reports
JF - Current Geriatrics Reports
IS - 3
ER -