Breast cancer and hormone-replacement therapy

Thomas Brunoski; Lynda H. Powell; Janine A. Blackman; Trudy L. Bush; K. S. Joseph; William D. Dupont; D. R. Wigg; Avrum Z. Bluming; Graham A. Colditz; Walter C. Willett; Frank E. Speizer

doi:10.1056/NEJM199511163332013

Breast cancer and hormone-replacement therapy

Thomas Brunoski, Lynda H. Powell, Janine A. Blackman, Trudy L. Bush, K. S. Joseph, William D. Dupont, D. R. Wigg, Avrum Z. Bluming, Graham A. Colditz, Walter C. Willett, Frank E. Speizer

Research output: Contribution to journal › Letter › peer-review

3 Scopus citations

Abstract

To the Editor: The data from the Nurses' Health Study, reported by Colditz et al. (June 15 issue),¹ show a significant increase in the risk of breast cancer with hormone-replacement therapy. I am at a loss, however, about how to counsel my patients on the basis of these data. The relative risks are presented, but there is no mention of the absolute risk, which would be of much value to patients facing a decision about taking hormones. The use of patient-years is confusing and counterintuitive for clinical purposes. In an attempt to obtain an overview of the data, I have.

Original language	English
Pages (from-to)	1355-1358
Number of pages	4
Journal	New England Journal of Medicine
Volume	333
Issue number	20
DOIs	https://doi.org/10.1056/NEJM199511163332013
State	Published - Nov 16 1995

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title = "Breast cancer and hormone-replacement therapy",

abstract = "To the Editor: The data from the Nurses' Health Study, reported by Colditz et al. (June 15 issue),1 show a significant increase in the risk of breast cancer with hormone-replacement therapy. I am at a loss, however, about how to counsel my patients on the basis of these data. The relative risks are presented, but there is no mention of the absolute risk, which would be of much value to patients facing a decision about taking hormones. The use of patient-years is confusing and counterintuitive for clinical purposes. In an attempt to obtain an overview of the data, I have.",

author = "Thomas Brunoski and Powell, {Lynda H.} and Blackman, {Janine A.} and Bush, {Trudy L.} and Joseph, {K. S.} and Dupont, {William D.} and Wigg, {D. R.} and Bluming, {Avrum Z.} and Colditz, {Graham A.} and Willett, {Walter C.} and Speizer, {Frank E.}",

year = "1995",

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doi = "10.1056/NEJM199511163332013",

language = "English",

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T1 - Breast cancer and hormone-replacement therapy

AU - Brunoski, Thomas

AU - Powell, Lynda H.

AU - Blackman, Janine A.

AU - Bush, Trudy L.

AU - Joseph, K. S.

AU - Dupont, William D.

AU - Wigg, D. R.

AU - Bluming, Avrum Z.

AU - Colditz, Graham A.

AU - Willett, Walter C.

AU - Speizer, Frank E.

PY - 1995/11/16

Y1 - 1995/11/16

N2 - To the Editor: The data from the Nurses' Health Study, reported by Colditz et al. (June 15 issue),1 show a significant increase in the risk of breast cancer with hormone-replacement therapy. I am at a loss, however, about how to counsel my patients on the basis of these data. The relative risks are presented, but there is no mention of the absolute risk, which would be of much value to patients facing a decision about taking hormones. The use of patient-years is confusing and counterintuitive for clinical purposes. In an attempt to obtain an overview of the data, I have.

AB - To the Editor: The data from the Nurses' Health Study, reported by Colditz et al. (June 15 issue),1 show a significant increase in the risk of breast cancer with hormone-replacement therapy. I am at a loss, however, about how to counsel my patients on the basis of these data. The relative risks are presented, but there is no mention of the absolute risk, which would be of much value to patients facing a decision about taking hormones. The use of patient-years is confusing and counterintuitive for clinical purposes. In an attempt to obtain an overview of the data, I have.

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DO - 10.1056/NEJM199511163332013

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VL - 333

SP - 1355

EP - 1358

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 20

ER -

Breast cancer and hormone-replacement therapy

Abstract

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