The equilibration of labeled water (H2 15O) with the exchangeable water pool of brain was examined during a single capillary transit. The labeled water did not equilibrate freely when cerebral blood flow (CBF) exceeded 20 (ml/100 gm)/min in the rhesus monkey. At normal CBF [.50 (ml/100 gm)/min] only 90% of the injected bolus freely equilibrated with brain. This value progressively declined as CBF increased.
|Number of pages||3|
|Journal||Archives of neurology|
|State||Published - Apr 1974|