Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression

Keyphrases

• Gene Expression 100%
• Brain-derived Neurotrophic Factor 100%
• Amyloidogenic Processing 100%
• SorLA 100%
• Alzheimer's Disease 40%
• Amyloid Precursor Protein 40%
• Primary Neurons 40%
• Gene Transcription 40%
• Wild Mice 20%
• Knock-in Mouse Model 20%
• Mouse Model 20%
• Overexpression 20%
• Disease-related 20%
• Physiological Role 20%
• Senile Plaques 20%
• Plaque Formation 20%
• Inducer 20%
• Cellular Processes 20%
• Molecular Pathways 20%
• Screening Approach 20%
• Receptor Gene 20%
• Extracellular Signal-regulated Kinase 20%
• Beneficial Effects 20%
• Negative Regulator 20%
• Receptor Expression 20%
• Mouse in Vivo 20%
• Huntington's Disease 20%
• Kinase Cascade 20%
• Protein Metabolism 20%
• Major Risk Factors 20%
• Intracellular Trafficking 20%
• Intracellular Processing 20%
• Amyloidogenic Peptides 20%
• Exogenous Application 20%
• A-type 20%
• Bdnf 20%
• Sorting Receptor 20%

Neuroscience

• Gene Expression 100%
• Brain-Derived Neurotrophic Factor 100%
• Amyloid Precursor Protein 60%
• Receptor 60%
• Alzheimer's Disease 40%
• In Vivo 40%
• Genetic Transcription 40%
• Senile Plaque 20%
• Kinase 20%
• Metabolic Pathway 20%
• Receptor Gene 20%
• Receptor Expression 20%
• Posttranslational Modification 20%
• Huntington's Disease 20%
• Intracellular Trafficking 20%
• Protein Targeting 20%