Bone Resorption Induced by Middle-Ear Implants

Michael D. Mcginn; Richard A. Chole; Steven P. Tinling

doi:10.1001/archotol.1986.03780060047006

Bone Resorption Induced by Middle-Ear Implants

Michael D. Mcginn
, Richard A. Chole
, Steven P. Tinling

Department of Otolaryngology

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The pressure produced by expanding aural cholesteatomas has been implicated as a causal factor in the induction of osteoclastic resorption of adjoining bone. This concept is supported by observations of osteoclastic bone resorption produced by expansive tympanic implants. We induced osteoclastic bone resorption in gerbils with tympanic implants of autologous and homologous cartilage, silicone rubber, and Teflon, which exerted pressure only by forces of gravity and surface tension. We estimated that the pressure exerted by these implants ranged from 2.1 × 10⁻³ to 8.0 × 10⁻³ dynes/sq cm (1.6 to 6.0 mm Hg). These pressures are within the range of pressures known to be exerted by cholesteatomas. (Arch Otolaryngol Head Neck Surg 1986;112:635-641)

Original language	English
Pages (from-to)	635-641
Number of pages	7
Journal	Archives of Otolaryngology--Head and Neck Surgery
Volume	112
Issue number	6
DOIs	https://doi.org/10.1001/archotol.1986.03780060047006
State	Published - Jun 1986

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title = "Bone Resorption Induced by Middle-Ear Implants",

abstract = "The pressure produced by expanding aural cholesteatomas has been implicated as a causal factor in the induction of osteoclastic resorption of adjoining bone. This concept is supported by observations of osteoclastic bone resorption produced by expansive tympanic implants. We induced osteoclastic bone resorption in gerbils with tympanic implants of autologous and homologous cartilage, silicone rubber, and Teflon, which exerted pressure only by forces of gravity and surface tension. We estimated that the pressure exerted by these implants ranged from 2.1 × 10−3 to 8.0 × 10−3 dynes/sq cm (1.6 to 6.0 mm Hg). These pressures are within the range of pressures known to be exerted by cholesteatomas. (Arch Otolaryngol Head Neck Surg 1986;112:635-641)",

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AU - Chole, Richard A.

AU - Tinling, Steven P.

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AB - The pressure produced by expanding aural cholesteatomas has been implicated as a causal factor in the induction of osteoclastic resorption of adjoining bone. This concept is supported by observations of osteoclastic bone resorption produced by expansive tympanic implants. We induced osteoclastic bone resorption in gerbils with tympanic implants of autologous and homologous cartilage, silicone rubber, and Teflon, which exerted pressure only by forces of gravity and surface tension. We estimated that the pressure exerted by these implants ranged from 2.1 × 10−3 to 8.0 × 10−3 dynes/sq cm (1.6 to 6.0 mm Hg). These pressures are within the range of pressures known to be exerted by cholesteatomas. (Arch Otolaryngol Head Neck Surg 1986;112:635-641)

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Bone Resorption Induced by Middle-Ear Implants

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