Bone marrow transplantation increases efficacy of central nervous system-directed enzyme replacement therapy in the murine model of globoid cell leukodystrophy

Keyphrases

• After Injection 10%
• Autosomal Recessive 10%
• Bone Marrow 10%
• Bone Marrow Transplantation 100%
• Central Nervous System 100%
• Enzyme Replacement Therapy 100%
• Galactocerebrosidase 30%
• Globoid Cell Leukodystrophy 100%
• Hematopoietic Stem Cell Transplantation 10%
• Intracerebroventricular Injection 10%
• Intrathecal Injection 10%
• Krabbe Disease 10%
• Lysosomal Enzymes 10%
• Motor Function 20%
• Murine Model 100%
• Myelin 10%
• Neurodegenerative Diseases 10%
• Neuroinflammation 20%
• Oligodendrocyte 10%
• Psychosine 30%
• Recombinant Enzyme 10%
• Supraphysiological 10%
• Synergistic Effect 10%
• Therapeutic Benefits 10%
• Therapeutic Effect 10%
• Toxic Metabolites 10%
• Twitcher Mouse 60%
• Umbilical Cord Blood 10%

Immunology and Microbiology

• Autosomal Recessive Inheritance 16%
• Bone Marrow Transplantation 100%
• Central Nervous System 100%
• Hematopoietic Stem Cell Transplantation 16%
• Lifespan 33%
• Metabolite 16%
• Motor Performance 33%
• Myelin 16%
• Twitcher Mouse 100%
• Umbilical Cord Blood 16%

Neuroscience

• Central Nervous System 100%
• Enzyme Replacement Therapy 100%
• Epileptic Absence 10%
• Galactosylceramidase 30%
• Hematopoietic Stem Cell 10%
• Intrathecal 10%
• Krabbe Disease 10%
• Leukodystrophy 100%
• Lysosome Enzyme 10%
• Myelin 10%
• Neurodegenerative Disorder 10%
• Oligodendrocyte 10%
• Psychosine 30%
• Recombinant Enzyme 10%