Bone marrow imaging in children

M. J. Siegel, G. D. Luker

Research output: Contribution to journalReview article

15 Scopus citations


MR imaging is a sensitive technique fur noninvasively evaluating bone marrow composition. During skeletal maturation, hematopoietic marrow is converted to fatty marrow. Knowledge of the normal conversion patterns is important if marrow pathology is to be detected. Alterations in bone marrow signal occur in a variety of disorders, including marrow hyperplasia, tumor infiltration, myeloid depletion, myelofibrosis, edema and ischemia. Qualitative analysis of signal intensity is often non-specific and the MR imaging findings need to be correlated with clinical history. Quantitative techniques have the potential to increase the specificity of MR imaging in the diagnosis of hematologic diseases in children.

Original languageEnglish
Pages (from-to)771-796
Number of pages26
JournalMagnetic Resonance Imaging Clinics of North America
Issue number4
StatePublished - Dec 9 1996

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