Bone cells: Biochemical and biological studies after enzymatic isolation

William A. Peck, Stanley J. Birge, Susan A. Fedak

Research output: Contribution to journalArticlepeer-review

222 Scopus citations

Abstract

Short-term incubation of rat calvaria in buffered crude collagenase permitted the isolation of morphologically intact cells that absorb vital dyes, contain alkaline phosphatase, and multiply in tissue culture. Freshly harvested cells were similar to whole bone segments in aerobic glucose metabolism.

Original languageEnglish
Pages (from-to)1476-1477
Number of pages2
JournalScience
Volume146
Issue number3650
DOIs
StatePublished - Jan 1 1964

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