TY - JOUR
T1 - Body fluid compartment changes following cardiopulmonary bypass in dogs
AU - Manning, Peter B.
AU - Morgan, Ross A.
AU - Coran, Arnold G.
AU - Polley, Theodore Z.
AU - Drongowski, Robert A.
AU - Buckley, John T.
AU - Behrendt, Douglas M.
PY - 1988/7
Y1 - 1988/7
N2 - To investigate whether pulsatile perfusion affects postoperative edema, we examined weight, total body water (TBW), and extracellular fluid (ECF) following cardiopulmonary bypass (CPB) in dogs using three different perfusion systems. Fourteen dogs were divided into three groups differing only in the perfusion system used: Sarns nonpulsatile and pulsatile roller pumps and a University of Texas pulsatile pump. Weight, TBW, and ECF were measured preoperatively and on postoperative days (POD) 1, 3, and 7. No significant differences were seen in body weight, TBW, or ECF between groups. Body TBW (percent of body weight) rose significantly (P=0.005) to 72% on POD 3 and 7. ECF (percent of body weight) rose to 58% by POD 7 (P=0.008). These three perfusion systems produced no differences in the pattern of postoperative body fluid distribution after CPB, suggesting that there is no advantage to pulsatile perfusion for the purpose of decreasing postoperative edema.
AB - To investigate whether pulsatile perfusion affects postoperative edema, we examined weight, total body water (TBW), and extracellular fluid (ECF) following cardiopulmonary bypass (CPB) in dogs using three different perfusion systems. Fourteen dogs were divided into three groups differing only in the perfusion system used: Sarns nonpulsatile and pulsatile roller pumps and a University of Texas pulsatile pump. Weight, TBW, and ECF were measured preoperatively and on postoperative days (POD) 1, 3, and 7. No significant differences were seen in body weight, TBW, or ECF between groups. Body TBW (percent of body weight) rose significantly (P=0.005) to 72% on POD 3 and 7. ECF (percent of body weight) rose to 58% by POD 7 (P=0.008). These three perfusion systems produced no differences in the pattern of postoperative body fluid distribution after CPB, suggesting that there is no advantage to pulsatile perfusion for the purpose of decreasing postoperative edema.
KW - Body fluid compartments
KW - Cardiopulmonary bypass
KW - Perfusion systems TBW (percent of body weight) rose significantly
UR - http://www.scopus.com/inward/record.url?scp=0023688534&partnerID=8YFLogxK
U2 - 10.1007/BF00189175
DO - 10.1007/BF00189175
M3 - Article
AN - SCOPUS:0023688534
SN - 0179-0358
VL - 3
SP - 351
EP - 353
JO - Pediatric Surgery International
JF - Pediatric Surgery International
IS - 5
ER -