TY - JOUR
T1 - Blood vessel deformations on microsecond time scales by ultrasonic cavitation
AU - Chen, Hong
AU - Kreider, Wayne
AU - Brayman, Andrew A.
AU - Bailey, Michael R.
AU - Matula, Thomas J.
PY - 2011/1/18
Y1 - 2011/1/18
N2 - Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.
AB - Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.
UR - http://www.scopus.com/inward/record.url?scp=78751503427&partnerID=8YFLogxK
U2 - 10.1103/PhysRevLett.106.034301
DO - 10.1103/PhysRevLett.106.034301
M3 - Article
AN - SCOPUS:78751503427
SN - 0031-9007
VL - 106
JO - Physical Review Letters
JF - Physical Review Letters
IS - 3
M1 - 034301
ER -