Blood pulse wave velocity measured by photoacoustic microscopy

Chenghung Yeh; Song Hu; Konstantin Maslov; Lihong V. Wang

doi:10.1117/12.2004232

Blood pulse wave velocity measured by photoacoustic microscopy

Chenghung Yeh
, Song Hu
, Konstantin Maslov
, Lihong V. Wang

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.

Original language	English
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2013
Publisher	SPIE
ISBN (Print)	9780819493507
DOIs	https://doi.org/10.1117/12.2004232
State	Published - Mar 4 2013
Event	Photons Plus Ultrasound: Imaging and Sensing 2013 - San Francisco, CA, United States Duration: Feb 3 2013 → Feb 5 2013

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8581
ISSN (Print)	1605-7422

Conference

Conference	Photons Plus Ultrasound: Imaging and Sensing 2013
Country/Territory	United States
City	San Francisco, CA
Period	02/3/13 → 02/5/13

Access to Document

10.1117/12.2004232

Cite this

@inproceedings{307c3bdd2137448c97cd4e73ee02574b,

title = "Blood pulse wave velocity measured by photoacoustic microscopy",

abstract = "Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.",

author = "Chenghung Yeh and Song Hu and Konstantin Maslov and Wang, \{Lihong V.\}",

year = "2013",

month = mar,

day = "4",

doi = "10.1117/12.2004232",

language = "English",

isbn = "9780819493507",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

booktitle = "Photons Plus Ultrasound",

note = "Photons Plus Ultrasound: Imaging and Sensing 2013 ; Conference date: 03-02-2013 Through 05-02-2013",

}

Yeh, C, Hu, S, Maslov, K & Wang, LV 2013, Blood pulse wave velocity measured by photoacoustic microscopy. in Photons Plus Ultrasound: Imaging and Sensing 2013., 85812C, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8581, SPIE, Photons Plus Ultrasound: Imaging and Sensing 2013, San Francisco, CA, United States, 02/3/13. https://doi.org/10.1117/12.2004232

Blood pulse wave velocity measured by photoacoustic microscopy. / Yeh, Chenghung; Hu, Song; Maslov, Konstantin et al.
Photons Plus Ultrasound: Imaging and Sensing 2013. SPIE, 2013. 85812C (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8581).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Blood pulse wave velocity measured by photoacoustic microscopy

AU - Yeh, Chenghung

AU - Hu, Song

AU - Maslov, Konstantin

AU - Wang, Lihong V.

PY - 2013/3/4

Y1 - 2013/3/4

N2 - Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.

AB - Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.

UR - https://www.scopus.com/pages/publications/84878090500

U2 - 10.1117/12.2004232

DO - 10.1117/12.2004232

M3 - Conference contribution

AN - SCOPUS:84878090500

SN - 9780819493507

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Photons Plus Ultrasound

PB - SPIE

T2 - Photons Plus Ultrasound: Imaging and Sensing 2013

Y2 - 3 February 2013 through 5 February 2013

ER -

Blood pulse wave velocity measured by photoacoustic microscopy

Abstract

Publication series

Conference

Access to Document

Other files and links

Fingerprint

Cite this