TY - JOUR
T1 - Biostatistics primer
T2 - What a clinician ought to know: Hazard ratios
AU - Barraclough, Helen
AU - Simms, Lorinda
AU - Govindan, Ramaswamy
PY - 2011/6
Y1 - 2011/6
N2 - Hazard ratios (HRs) are used commonly to report results from randomized clinical trials in oncology. However, they remain one of the most perplexing concepts for clinicians. A good understanding of HRs is needed to effectively interpret the medical literature to make important treatment decisions. This article provides clear guidelines to clinicians about how to appropriately interpret HRs. While this article focuses on the commonly used methods, the authors acknowledge that other statistical methods exist for analyzing survival data.
AB - Hazard ratios (HRs) are used commonly to report results from randomized clinical trials in oncology. However, they remain one of the most perplexing concepts for clinicians. A good understanding of HRs is needed to effectively interpret the medical literature to make important treatment decisions. This article provides clear guidelines to clinicians about how to appropriately interpret HRs. While this article focuses on the commonly used methods, the authors acknowledge that other statistical methods exist for analyzing survival data.
KW - Biostatistics
KW - Hazard ratio
KW - Proportional hazards
KW - Survival analysis
UR - http://www.scopus.com/inward/record.url?scp=79958078253&partnerID=8YFLogxK
U2 - 10.1097/JTO.0b013e31821b10ab
DO - 10.1097/JTO.0b013e31821b10ab
M3 - Article
C2 - 21623277
AN - SCOPUS:79958078253
SN - 1556-0864
VL - 6
SP - 978
EP - 982
JO - Journal of Thoracic Oncology
JF - Journal of Thoracic Oncology
IS - 6
ER -