Biostatistics primer: What a clinician ought to know: Hazard ratios

Helen Barraclough, Lorinda Simms, Ramaswamy Govindan

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Hazard ratios (HRs) are used commonly to report results from randomized clinical trials in oncology. However, they remain one of the most perplexing concepts for clinicians. A good understanding of HRs is needed to effectively interpret the medical literature to make important treatment decisions. This article provides clear guidelines to clinicians about how to appropriately interpret HRs. While this article focuses on the commonly used methods, the authors acknowledge that other statistical methods exist for analyzing survival data.

Original languageEnglish
Pages (from-to)978-982
Number of pages5
JournalJournal of Thoracic Oncology
Volume6
Issue number6
DOIs
StatePublished - Jun 2011

Keywords

  • Biostatistics
  • Hazard ratio
  • Proportional hazards
  • Survival analysis

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