Biologics for chronic rhinosinusitis with nasal polyps: Economics and ethics

Lauren T. Roland, Alan Regenberg, Amber U. Luong, Sarah K. Wise, Elina Toskala, Kent K. Lam, Joshua M. Levy, Christine B. Franzese, Kristine Smith, Jean Kim

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Biologics have recently been approved for use in chronic rhinosinusitis with nasal polyps patients. While effective in controlling disease on subjective and objective short-term outcome measures, limited data suggest that biologics have the potential to be used long term. The current wholesale acquisition costs for biologics are quite high. Widespread, prolonged use of these medications may create a large burden to our healthcare system. Cost-effectiveness analyses, particularly for specific patient cohorts, are needed to determine appropriate use of these medications. The ethics of patient preference of various treatment options, counseling regarding side effect profiles, and healthcare economics also need to be addressed.

Original languageEnglish
Pages (from-to)1524-1528
Number of pages5
JournalInternational Forum of Allergy and Rhinology
Issue number11
StatePublished - Nov 2021


  • chronic rhinosinusitis
  • medical therapy of chronic rhinosinusitis
  • rhinosinusitis


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