Biocompatible interface films deposited within porous polymers by atomic layer deposition (ALD)

Xinhua Liang; Aaron D. Lynn; David M. King; Stephanie J. Bryant; Alan W. Weimer

doi:10.1021/am9003667

Biocompatible interface films deposited within porous polymers by atomic layer deposition (ALD)

Xinhua Liang
, Aaron D. Lynn
, David M. King
, Stephanie J. Bryant
, Alan W. Weimer

Department of Energy, Environmental & Chemical Engineering

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Ultrathin ceramic films were deposited throughout highly porous poly(styrene-divinylbenzene) (PS-DVB) particles using a low-temperature atomic layer deposition (ALD) process. Alumina and titania films were deposited by alternating reactions of trimethylaluminum and H ₂O at 33 °C and of titanium tetrachloride and H ₂O ₂ (50 wt % in H ₂O) at 100 °C, respectively. Analytical characterization revealed that conformal alumina and titania films were grown on internal and external polymer surfaces. The improved bioactivity of the polymer substrates was revealed on the basis of the formation of hydroxyapatite (HA) in simulated body fluid. The accelerated formation of HA on the ALD-modified polymer surface was caused by the negatively charged surface provided by the ultrathin ceramic interface. The potential for ALD films to support cell attachment was demonstrated.

Original language	English
Pages (from-to)	1988-1995
Number of pages	8
Journal	ACS Applied Materials and Interfaces
Volume	1
Issue number	9
DOIs	https://doi.org/10.1021/am9003667
State	Published - Sep 30 2009

Keywords

atomic layer deposition (ALD)
cell adhesion
ceramic
hydroxyapatite (HA)
interface film
polymer

Access to Document

10.1021/am9003667

Cite this

@article{943e861cd54d47518a8ec6dfba253c86,

title = "Biocompatible interface films deposited within porous polymers by atomic layer deposition (ALD)",

abstract = "Ultrathin ceramic films were deposited throughout highly porous poly(styrene-divinylbenzene) (PS-DVB) particles using a low-temperature atomic layer deposition (ALD) process. Alumina and titania films were deposited by alternating reactions of trimethylaluminum and H 2O at 33 °C and of titanium tetrachloride and H 2O 2 (50 wt \% in H 2O) at 100 °C, respectively. Analytical characterization revealed that conformal alumina and titania films were grown on internal and external polymer surfaces. The improved bioactivity of the polymer substrates was revealed on the basis of the formation of hydroxyapatite (HA) in simulated body fluid. The accelerated formation of HA on the ALD-modified polymer surface was caused by the negatively charged surface provided by the ultrathin ceramic interface. The potential for ALD films to support cell attachment was demonstrated.",

keywords = "atomic layer deposition (ALD), cell adhesion, ceramic, hydroxyapatite (HA), interface film, polymer",

author = "Xinhua Liang and Lynn, \{Aaron D.\} and King, \{David M.\} and Bryant, \{Stephanie J.\} and Weimer, \{Alan W.\}",

year = "2009",

month = sep,

day = "30",

doi = "10.1021/am9003667",

language = "English",

volume = "1",

pages = "1988--1995",

journal = "ACS Applied Materials and Interfaces",

issn = "1944-8244",

number = "9",

}

TY - JOUR

T1 - Biocompatible interface films deposited within porous polymers by atomic layer deposition (ALD)

AU - Liang, Xinhua

AU - Lynn, Aaron D.

AU - King, David M.

AU - Bryant, Stephanie J.

AU - Weimer, Alan W.

PY - 2009/9/30

Y1 - 2009/9/30

N2 - Ultrathin ceramic films were deposited throughout highly porous poly(styrene-divinylbenzene) (PS-DVB) particles using a low-temperature atomic layer deposition (ALD) process. Alumina and titania films were deposited by alternating reactions of trimethylaluminum and H 2O at 33 °C and of titanium tetrachloride and H 2O 2 (50 wt % in H 2O) at 100 °C, respectively. Analytical characterization revealed that conformal alumina and titania films were grown on internal and external polymer surfaces. The improved bioactivity of the polymer substrates was revealed on the basis of the formation of hydroxyapatite (HA) in simulated body fluid. The accelerated formation of HA on the ALD-modified polymer surface was caused by the negatively charged surface provided by the ultrathin ceramic interface. The potential for ALD films to support cell attachment was demonstrated.

AB - Ultrathin ceramic films were deposited throughout highly porous poly(styrene-divinylbenzene) (PS-DVB) particles using a low-temperature atomic layer deposition (ALD) process. Alumina and titania films were deposited by alternating reactions of trimethylaluminum and H 2O at 33 °C and of titanium tetrachloride and H 2O 2 (50 wt % in H 2O) at 100 °C, respectively. Analytical characterization revealed that conformal alumina and titania films were grown on internal and external polymer surfaces. The improved bioactivity of the polymer substrates was revealed on the basis of the formation of hydroxyapatite (HA) in simulated body fluid. The accelerated formation of HA on the ALD-modified polymer surface was caused by the negatively charged surface provided by the ultrathin ceramic interface. The potential for ALD films to support cell attachment was demonstrated.

KW - atomic layer deposition (ALD)

KW - cell adhesion

KW - ceramic

KW - hydroxyapatite (HA)

KW - interface film

KW - polymer

UR - https://www.scopus.com/pages/publications/77951639977

U2 - 10.1021/am9003667

DO - 10.1021/am9003667

M3 - Article

C2 - 20355824

AN - SCOPUS:77951639977

SN - 1944-8244

VL - 1

SP - 1988

EP - 1995

JO - ACS Applied Materials and Interfaces

JF - ACS Applied Materials and Interfaces

IS - 9

ER -

Biocompatible interface films deposited within porous polymers by atomic layer deposition (ALD)

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this