Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Lydia Ann Harris; Brandon D. Kayser; Consuelo Cefalo; Luca Marini; Jeramie D. Watrous; Jeffrey Ding; Mohit Jain; Jeffrey G. McDonald; Bonne M. Thompson; Elisa Fabbrini; J. Christopher Eagon; Bruce W. Patterson; Bettina Mittendorfer; Geltrude Mingrone; Samuel Klein

doi:10.1016/j.cmet.2019.09.002

Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Lydia Ann Harris
, Brandon D. Kayser
, Consuelo Cefalo
, Luca Marini
, Jeramie D. Watrous
, Jeffrey Ding
, Mohit Jain
, Jeffrey G. McDonald
, Bonne M. Thompson
, Elisa Fabbrini
, J. Christopher Eagon
, Bruce W. Patterson
, Bettina Mittendorfer
, Geltrude Mingrone
, Samuel Klein

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

Original language	English
Pages (from-to)	855-864.e3
Journal	Cell metabolism
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/j.cmet.2019.09.002
State	Published - Nov 5 2019

Keywords

bariatric surgery
insulin sensitivity
obesity

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10.1016/j.cmet.2019.09.002

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Harris, L. A., Kayser, B. D., Cefalo, C., Marini, L., Watrous, J. D., Ding, J., Jain, M., McDonald, J. G., Thompson, B. M., Fabbrini, E., Eagon, J. C., Patterson, B. W., Mittendorfer, B., Mingrone, G., & Klein, S. (2019). Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass. Cell metabolism, 30(5), 855-864.e3. https://doi.org/10.1016/j.cmet.2019.09.002

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title = "Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass",

abstract = "Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.",

keywords = "bariatric surgery, insulin sensitivity, obesity",

author = "Harris, \{Lydia Ann\} and Kayser, \{Brandon D.\} and Consuelo Cefalo and Luca Marini and Watrous, \{Jeramie D.\} and Jeffrey Ding and Mohit Jain and McDonald, \{Jeffrey G.\} and Thompson, \{Bonne M.\} and Elisa Fabbrini and Eagon, \{J. Christopher\} and Patterson, \{Bruce W.\} and Bettina Mittendorfer and Geltrude Mingrone and Samuel Klein",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = nov,

day = "5",

doi = "10.1016/j.cmet.2019.09.002",

language = "English",

volume = "30",

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Harris, LA, Kayser, BD, Cefalo, C, Marini, L, Watrous, JD, Ding, J, Jain, M, McDonald, JG, Thompson, BM, Fabbrini, E, Eagon, JC , Patterson, BW, Mittendorfer, B, Mingrone, G & Klein, S 2019, 'Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass', Cell metabolism, vol. 30, no. 5, pp. 855-864.e3. https://doi.org/10.1016/j.cmet.2019.09.002

TY - JOUR

T1 - Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

AU - Harris, Lydia Ann

AU - Kayser, Brandon D.

AU - Cefalo, Consuelo

AU - Marini, Luca

AU - Watrous, Jeramie D.

AU - Ding, Jeffrey

AU - Jain, Mohit

AU - McDonald, Jeffrey G.

AU - Thompson, Bonne M.

AU - Fabbrini, Elisa

AU - Eagon, J. Christopher

AU - Patterson, Bruce W.

AU - Mittendorfer, Bettina

AU - Mingrone, Geltrude

AU - Klein, Samuel

PY - 2019/11/5

Y1 - 2019/11/5

N2 - Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

AB - Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

KW - bariatric surgery

KW - insulin sensitivity

KW - obesity

UR - https://www.scopus.com/pages/publications/85074167270

U2 - 10.1016/j.cmet.2019.09.002

DO - 10.1016/j.cmet.2019.09.002

M3 - Article

C2 - 31588013

AN - SCOPUS:85074167270

SN - 1550-4131

VL - 30

SP - 855-864.e3

JO - Cell metabolism

JF - Cell metabolism

IS - 5

ER -

Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Abstract

Keywords

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