Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Lydia Ann Harris; Brandon D. Kayser; Consuelo Cefalo; Luca Marini; Jeramie D. Watrous; Jeffrey Ding; Mohit Jain; Jeffrey G. McDonald; Bonne M. Thompson; Elisa Fabbrini; J. Christopher Eagon; Bruce W. Patterson; Bettina Mittendorfer; Geltrude Mingrone; Samuel Klein

doi:10.1016/j.cmet.2019.09.002

Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Lydia Ann Harris, Brandon D. Kayser, Consuelo Cefalo, Luca Marini, Jeramie D. Watrous, Jeffrey Ding, Mohit Jain, Jeffrey G. McDonald, Bonne M. Thompson, Elisa Fabbrini, J. Christopher Eagon, Bruce W. Patterson, Bettina Mittendorfer, Geltrude Mingrone, Samuel Klein

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

Original language	English
Pages (from-to)	855-864.e3
Journal	Cell metabolism
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/j.cmet.2019.09.002
State	Published - Nov 5 2019

Keywords

bariatric surgery
insulin sensitivity
obesity

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10.1016/j.cmet.2019.09.002

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Harris, L. A., Kayser, B. D., Cefalo, C., Marini, L., Watrous, J. D., Ding, J., Jain, M., McDonald, J. G., Thompson, B. M., Fabbrini, E., Eagon, J. C., Patterson, B. W., Mittendorfer, B., Mingrone, G., & Klein, S. (2019). Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass. Cell metabolism, 30(5), 855-864.e3. https://doi.org/10.1016/j.cmet.2019.09.002

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title = "Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass",

abstract = "Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.",

keywords = "bariatric surgery, insulin sensitivity, obesity",

author = "Harris, {Lydia Ann} and Kayser, {Brandon D.} and Consuelo Cefalo and Luca Marini and Watrous, {Jeramie D.} and Jeffrey Ding and Mohit Jain and McDonald, {Jeffrey G.} and Thompson, {Bonne M.} and Elisa Fabbrini and Eagon, {J. Christopher} and Patterson, {Bruce W.} and Bettina Mittendorfer and Geltrude Mingrone and Samuel Klein",

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year = "2019",

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doi = "10.1016/j.cmet.2019.09.002",

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Harris, LA, Kayser, BD, Cefalo, C, Marini, L, Watrous, JD, Ding, J, Jain, M, McDonald, JG, Thompson, BM, Fabbrini, E, Eagon, JC , Patterson, BW, Mittendorfer, B, Mingrone, G & Klein, S 2019, 'Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass', Cell metabolism, vol. 30, no. 5, pp. 855-864.e3. https://doi.org/10.1016/j.cmet.2019.09.002

TY - JOUR

T1 - Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

AU - Harris, Lydia Ann

AU - Kayser, Brandon D.

AU - Cefalo, Consuelo

AU - Marini, Luca

AU - Watrous, Jeramie D.

AU - Ding, Jeffrey

AU - Jain, Mohit

AU - McDonald, Jeffrey G.

AU - Thompson, Bonne M.

AU - Fabbrini, Elisa

AU - Eagon, J. Christopher

AU - Patterson, Bruce W.

AU - Mittendorfer, Bettina

AU - Mingrone, Geltrude

AU - Klein, Samuel

PY - 2019/11/5

Y1 - 2019/11/5

N2 - Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

AB - Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

KW - bariatric surgery

KW - insulin sensitivity

KW - obesity

UR - http://www.scopus.com/inward/record.url?scp=85074167270&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2019.09.002

DO - 10.1016/j.cmet.2019.09.002

M3 - Article

C2 - 31588013

AN - SCOPUS:85074167270

SN - 1550-4131

VL - 30

SP - 855-864.e3

JO - Cell metabolism

JF - Cell metabolism

IS - 5

ER -

Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Abstract

Keywords

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