Bictegravir-Based Antiretroviral Therapy-Associated Accelerated Hyperglycemia and Diabetes Mellitus

Nathanial S. Nolan, Samantha Adamson, Dominic Reeds, Jane A. O'Halloran

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART) is first line for treatment of people with human immunodeficiency virus (PWH). Emerging data suggest the possibility of adverse metabolic effects of these medications. We describe 3 cases in which PWH developed hyperglycemia and ketoacidosis within months of being switched to bictegravir-based ART.

Original languageEnglish
Article numberofab077
JournalOpen Forum Infectious Diseases
Volume8
Issue number5
DOIs
StatePublished - May 1 2021

Keywords

  • HIV
  • bictegravir
  • diabetes
  • hyperglycemia
  • integrase strand transfer inhibitors

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