Bi-layer blood vessel mimicking microfluidic platform for antitumor drug screening based on co-culturing 3D tumor spheroids and endothelial layers

Keyphrases

• Microfluidic Device 100%
• Blood Vessels 100%
• Microfluidic Platform 100%
• Endothelial Layer 100%
• Multicellular Tumor Spheroids 100%
• Antitumor Drug Screening 100%
• Tumor 66%
• Paclitaxel 66%
• Matrigel 66%
• Drug Testing 66%
• Optical Coherence Tomography 66%
• Polydimethylsiloxane 66%
• Tumor Cells 33%
• Endothelial Cells 33%
• Confocal Microscopy 33%
• High Concentration 33%
• Endothelial Monolayer 33%
• Tumor Model 33%
• Drug Treatment 33%
• Optical Characterization 33%
• Cell Migration 33%
• Microenvironment 33%
• Drug Screening 33%
• Anticancer Drugs 33%
• Two-dimensional Cell Culture 33%
• Long Distance 33%
• Oxygen Supply 33%
• Volumetric Change 33%
• Two-dimensional Culture 33%
• Blood Tumors 33%
• Drug Screening System 33%
• Traditional Drugs 33%
• Water Supply 33%
• Tumor Spheroids 33%
• Basal Channels 33%
• Physiological Microenvironment 33%
• Nutrition Supply 33%
• Semipermeable Membrane 33%
• Biomimic 33%
• Exchange Area 33%

Medicine and Dentistry

• Drug Screening 100%
• Vascular Bundle 100%
• Tumor Spheroid 100%
• Anticarcinogen 100%
• Drug Screening 100%
• Neoplasm 50%
• Endothelial Cell 50%
• Paclitaxel 50%
• Optical Coherence Tomography 50%
• Matrigel 50%
• Dimeticone 50%
• Drug Therapy 25%
• Tumor Cell 25%
• Confocal Microscopy 25%
• Cell Culture 25%
• Tumor Model 25%
• Vascular Tissue Neoplasm 25%
• Cell Migration 25%
• Nutrition 25%

Engineering

• Microfluidic Platform 100%
• Microfluidic Device 100%
• Microenvironments 66%
• Two Dimensional 66%
• Polydimethylsiloxane 66%
• Confocal Microscopy 33%
• Semipermeable Membrane 33%
• Monolayers 33%