Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus

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Abstract

Respiratory viruses other than rhinovirus or respiratory syncytial virus, including human metapneumovirus, influenza virus, and human bocavirus, are important pathogens in acute wheezing illness and asthma exacerbations in young children. Whether infection with these viruses in early life is associated with recurrent wheezing and/or asthma is not fully investigated, although there are data to suggest children with human metapneumovirus lower respiratory tract infection may have a higher likelihood of subsequent and recurrent wheezing several years after initial infection.

Original languageEnglish
Pages (from-to)391-401
Number of pages11
JournalImmunology and Allergy Clinics of North America
Volume39
Issue number3
DOIs
StatePublished - Aug 2019

Keywords

  • Asthma
  • Bocavirus
  • Human metapneumovirus
  • Influenza virus
  • Wheezing

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