TY - JOUR
T1 - Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma
T2 - The Role of Metapneumovirus, Bocavirus and Influenza Virus
AU - Coverstone, Andrea M.
AU - Wang, Leyao
AU - Sumino, Kaharu
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/8
Y1 - 2019/8
N2 - Respiratory viruses other than rhinovirus or respiratory syncytial virus, including human metapneumovirus, influenza virus, and human bocavirus, are important pathogens in acute wheezing illness and asthma exacerbations in young children. Whether infection with these viruses in early life is associated with recurrent wheezing and/or asthma is not fully investigated, although there are data to suggest children with human metapneumovirus lower respiratory tract infection may have a higher likelihood of subsequent and recurrent wheezing several years after initial infection.
AB - Respiratory viruses other than rhinovirus or respiratory syncytial virus, including human metapneumovirus, influenza virus, and human bocavirus, are important pathogens in acute wheezing illness and asthma exacerbations in young children. Whether infection with these viruses in early life is associated with recurrent wheezing and/or asthma is not fully investigated, although there are data to suggest children with human metapneumovirus lower respiratory tract infection may have a higher likelihood of subsequent and recurrent wheezing several years after initial infection.
KW - Asthma
KW - Bocavirus
KW - Human metapneumovirus
KW - Influenza virus
KW - Wheezing
UR - http://www.scopus.com/inward/record.url?scp=85065558332&partnerID=8YFLogxK
U2 - 10.1016/j.iac.2019.03.007
DO - 10.1016/j.iac.2019.03.007
M3 - Review article
C2 - 31284928
AN - SCOPUS:85065558332
SN - 0889-8561
VL - 39
SP - 391
EP - 401
JO - Immunology and Allergy Clinics of North America
JF - Immunology and Allergy Clinics of North America
IS - 3
ER -