Better Together: B7S1 Checkpoint Blockade Synergizes with anti-PD1

Melissa A. Meyer, David G. DeNardo

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

T cell checkpoint blockades can produce durable clinical responses, but only some patients and cancer types respond. In this issue of Immunity, Li et al. (2018) show B7S1-B7S1R signaling additionally regulates CD8+ T cell responses by working with the PD1-PDL1 checkpoint to block anti-tumor immunity. T cell checkpoint blockades can produce durable clinical responses, but only some patients and cancer types respond. In this issue of Immunity, Li et al. (2018) show B7S1-B7S1R signaling additionally regulates CD8+ T cell responses by working with the PD1-PDL1 checkpoint to block anti-tumor immunity.

Original languageEnglish
Pages (from-to)621-623
Number of pages3
JournalImmunity
Volume48
Issue number4
DOIs
StatePublished - Apr 17 2018

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