Benefits of Optimizing Heart Failure Medication Dosage

Sandra Oliver-McNeil; Margaret Bowers; Shane J. LaRue; Justin Vader; Adam D. DeVore; Bradi B. Granger

doi:10.1016/j.nurpra.2020.04.018

Benefits of Optimizing Heart Failure Medication Dosage

Sandra Oliver-McNeil
, Margaret Bowers
, Shane J. LaRue
, Justin Vader
, Adam D. DeVore
, Bradi B. Granger

Research output: Contribution to journal › Article › peer-review

Abstract

Heart failure is the leading cause of hospitalizations and readmissions. Guideline-directed medical therapy is the cornerstone to improving outcomes, but less than 20% of patients with heart failure marked by reduced ejection fraction receive target doses. This report reviews the neurohormonal cascade that occurs in heart failure and the role of guideline-directed medical therapy based on the results of landmark trials. In addition, evidence-based strategies to up-titrate medications are described. Nurse practitioners are in an optimal situation to titrate guideline therapy with frequent follow-up and monitoring.

Original language	English
Pages (from-to)	498-503
Number of pages	6
Journal	Journal for Nurse Practitioners
Volume	16
Issue number	7
DOIs	https://doi.org/10.1016/j.nurpra.2020.04.018
State	Published - Jul 1 2020

Keywords

HFrEF
guideline-directed medical therapy (GDMT)
heart failure guidelines
postdischarge care transition

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10.1016/j.nurpra.2020.04.018

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title = "Benefits of Optimizing Heart Failure Medication Dosage",

abstract = "Heart failure is the leading cause of hospitalizations and readmissions. Guideline-directed medical therapy is the cornerstone to improving outcomes, but less than 20\% of patients with heart failure marked by reduced ejection fraction receive target doses. This report reviews the neurohormonal cascade that occurs in heart failure and the role of guideline-directed medical therapy based on the results of landmark trials. In addition, evidence-based strategies to up-titrate medications are described. Nurse practitioners are in an optimal situation to titrate guideline therapy with frequent follow-up and monitoring.",

keywords = "HFrEF, guideline-directed medical therapy (GDMT), heart failure guidelines, postdischarge care transition",

author = "Sandra Oliver-McNeil and Margaret Bowers and LaRue, \{Shane J.\} and Justin Vader and DeVore, \{Adam D.\} and Granger, \{Bradi B.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

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doi = "10.1016/j.nurpra.2020.04.018",

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AU - Oliver-McNeil, Sandra

AU - Bowers, Margaret

AU - LaRue, Shane J.

AU - Vader, Justin

AU - DeVore, Adam D.

AU - Granger, Bradi B.

PY - 2020/7/1

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AB - Heart failure is the leading cause of hospitalizations and readmissions. Guideline-directed medical therapy is the cornerstone to improving outcomes, but less than 20% of patients with heart failure marked by reduced ejection fraction receive target doses. This report reviews the neurohormonal cascade that occurs in heart failure and the role of guideline-directed medical therapy based on the results of landmark trials. In addition, evidence-based strategies to up-titrate medications are described. Nurse practitioners are in an optimal situation to titrate guideline therapy with frequent follow-up and monitoring.

KW - HFrEF

KW - guideline-directed medical therapy (GDMT)

KW - heart failure guidelines

KW - postdischarge care transition

UR - https://www.scopus.com/pages/publications/85084732017

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SP - 498

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JO - Journal for Nurse Practitioners

JF - Journal for Nurse Practitioners

IS - 7

ER -

Benefits of Optimizing Heart Failure Medication Dosage

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Keywords

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