BEAD-BASED ELISA ACCELERATED VIA SURFACE ACOUSTIC WAVE-DRIVEN MIXING FLOW

  • Shuai Zhang
  • , Lei Zhang
  • , Kha Nguyen
  • , Cécile Floer
  • , James Friend

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We report the ability to improve bead-based sandwich enzyme-linked immunosorbent assays (ELISA) using surface acoustic wave-driven recirculatory sample mixing, reducing the time required from over thirty minutes to two minutes and improving the sensitivity by a factor of two. This may enable its use in point-of-care applications.

Original languageEnglish
Title of host publicationMicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages687-688
Number of pages2
ISBN (Electronic)9781733419048
StatePublished - 2022
Event26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 - Hybrid, Hangzhou, China
Duration: Oct 23 2022Oct 27 2022

Publication series

NameMicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022
Country/TerritoryChina
CityHybrid, Hangzhou
Period10/23/2210/27/22

Keywords

  • acoustofluidics
  • antibody binding
  • ELISA
  • micromixing

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