Basic Genetics and Epigenetics of Childhood Lung Disease

Jennifer Wambach; Bimal Pankaj Chaudhari; Aaron Hamvas

doi:10.1016/B978-0-323-44887-1.00003-1

Basic Genetics and Epigenetics of Childhood Lung Disease

Jennifer Wambach, Bimal Pankaj Chaudhari, Aaron Hamvas

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Childhood disease results from the interplay of genetic, environmental, and developmental factors. The rapid development of DNA technologies has unmasked the genetic diversity of individuals, almost all of which is not functionally significant, making it difficult to identify which variants might be contributing to phenotype. This chapter reviews genetic terminology and provides an overview of the strengths and limitations of currently available genetic testing and interpretation.

Original language	English
Title of host publication	Kendig's Disorders of the Respiratory Tract in Children
Publisher	Elsevier Inc.
Pages	40-48.e2
ISBN (Electronic)	9780323555951
ISBN (Print)	9780323448871
DOIs	https://doi.org/10.1016/B978-0-323-44887-1.00003-1
State	Published - 2019

Keywords

Exome sequencing
Genetic association studies
Genetic variation
Genome sequencing
Phenotype

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10.1016/B978-0-323-44887-1.00003-1

Cite this

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KW - Genetic association studies

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KW - Genome sequencing

KW - Phenotype

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ER -

Basic Genetics and Epigenetics of Childhood Lung Disease

Abstract

Keywords

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